Maltese Cross Sign Nephrotic Syndrome

He has a medical history of opioid use disorder with prior hospitalizations for a heroin.

Maltese cross sign nephrotic syndrome. Can be secondary to. The following are baseline essential investigations urine sample shows proteinuria. Large amounts of blood in nephritic. This can lead to a range of problems including swelling of body tissues and a greater chance of catching infections.

Fatty casts with maltese cross sign. There are two classifications of nephrotic syndrome. Treat underlying etiology in secondary causes. To watch this and all of joe gilboy pa c s video lessons you must be a member.

Focal segmental glomerulosclerosis. Normal in nephrotic but high in nephritic hematuria. Urinalysis demonstrates 4 protein and fatty casts with maltese cross sign. Acute poststreptococcal glomerulonephritis.

Lipid droplets associated with gross proteinuria are round and translucent without internal structure whereas the particles in our patient were of roundish to polygonal shape colourless and had a nucleus like centre a pattern which. Fatty casts with maltese cross sign. Although nephrotic syndrome can affect people of any age it s usually first diagnosed in children aged between 2 and 5 years old. Maltese crosses are due to cholesterol which is increased in nephrotic syndrome.

10 8 in nephrotic vs. 4 in nephrotic vs. Microscopy will show dysmorphic rbcs occasional rbc and granular casts spot urine ratio. Notably our patient had only moderate proteinuria no clinical signs of a nephrotic syndrome and the arms of the maltese crosses were asymmetric and irregular.

Formed by the adhesion of metabolic breakdown products or drug. Podocyte injury or decreased glomerular filtration barrier integrity. It is also examined. It affects more boys than girls.

The classic maltese cross pattern is evident in fatty casts with polarized microscopy because of the birefringence of the lipid. Members can log in here or join now. If cholesterol or cholesterol esters are present they are associated with the maltese cross sign under polarized light. Severe proteinuria 3 5 g day.

Hypoalbuminemia hyperlipidemia and lipiduria. They are pathognomonic for high urinary protein nephrotic syndrome. The urinary sediment showed fatty casts panel a with typical maltese crosses under polarized light panel b and was otherwise unremarkable with no sign of nephritis. In nephrotic syndrome many additional types of cast exist including broad and waxy casts if the condition is chronic.

Patient will present as a 26 year old man who presents with hematuria periorbital edema and jaundice.